Central Cemento-Ossifying Fibroma: A Case Report

of mineralized substances, which may be bony or cementum like in appearance. The lesion, termed as cemento-ossifying fibroma, has been regarded as an osteogenic neoplasm. The fibrous dysplasia in which the normal bone structure is replaced by collagenous tissue is normally regarded as non-neoplastic. The cemento-ossifying fibromas (COF), in some cases has been demarcated into ossifying and cementifying fibromas, based on the tissue content of encapsulated neoplasms appearing as bone and/or cementum [1]. COF is most commonly diagnosed in the third and fourth decades of age and possesses a clear-cut female predilection (Female: Male ratio being 4:1) [1-6]. The tumor appears as intrabony slow growing asymptomatic mass causing expansion of cortical plates, displacement of root and facial deformity. Radiologically, COF appears radiolucent with varying degree of radio opacity depending upon the degree of calcification. Histopathological picture reveals fibro-collagenous connective tissue with proliferating plump fibroblast cell and osteoid /cementoid mass. The management comprises of surgical resection involving enucleation via bone bed curettage. Due to significant overlap of clinical, radiological and histopathological criteria, sub-classification of fibro-osseous lesions are difficult which often leads to the confusion in diagnosis and therefore management. The present article reports one COF case involving the left mandible and with its clinical, radiological and histological findings.